Cisplatin product monograph pdf

Product monograph pr paclitaxel injection usp paclitaxel injection, 6 mgml therapeutic classification antineoplastic agent. The name of your medicine is cisplatin 1 mgml concentrate for solution for. Appropriate management of therapy and complications is possible only when adequate. When paclitaxel is given before cisplatin, the safety profile of paclitaxel is consistent with that reported. In the absence of compatibility studies, this medicinal product must not be. Summary product information, route of administration. Drug name mechanism of action and pharmacokinetics indications and status adverse effects dosing administration. Delayed onset hearing loss has been reported in pediatric patients.

Platinol cisplatin for injection, usp should be administered under the supervision. Cisplatin injection description clinical pharmacology fda. Adjunct to other antineoplastic agents for the treatment of metastatic testicular tumors including nonseminomatous testicular carcinoma, seminoma testis, and extragonadal germcell tumors in patients who have already received appropriate surgery andor radiation therapy. Alimta pemetrexed disodium in combination with cisplatin is indicated for the firstline treatment of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery. Ototoxicity may be more pronounced in younger children. Highlights of prescribing information these highlights. Product monograph page 8 of 61 adverse reactions adverse drug reaction overview. Platinolaq cisplatin injection prescribing information.

Cisplatin injection cisplatin 50 mg50 ml 1 mgml100 mg100. Oxaliplatin also demonstrates in vitro activity against cisplatin. These complexes are slowly eliminated with a halflife of 5 days or more. However, the platinum from cisplatin becomes bound to plasma proteins. The risk of ototoxicity may be increased by concomitant administration of other ototoxic drugs e.